Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Identifieur interne : 000971 ( Main/Exploration ); précédent : 000970; suivant : 000972Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Auteurs : Alan Mackay [Royaume-Uni] ; Anna Burford [Royaume-Uni] ; Diana Carvalho [Royaume-Uni] ; Elisa Izquierdo [Royaume-Uni] ; Janat Fazal-Salom [Royaume-Uni] ; Kathryn R. Taylor [Royaume-Uni, États-Unis] ; Lynn Bjerke [Royaume-Uni] ; Matthew Clarke [Royaume-Uni] ; Mara Vinci [Royaume-Uni] ; Meera Nandhabalan [Royaume-Uni] ; Sara Temelso [Royaume-Uni] ; Sergey Popov [Royaume-Uni] ; Valeria Molinari [Royaume-Uni] ; Pichai Raman [États-Unis] ; Angela J. Waanders [États-Unis] ; Harry J. Han [États-Unis] ; Saumya Gupta [Suisse] ; Lynley Marshall [Royaume-Uni] ; Stergios Zacharoulis [Royaume-Uni] ; Sucheta Vaidya [Royaume-Uni] ; Henry C. Mandeville [Royaume-Uni] ; Leslie R. Bridges [Royaume-Uni] ; Andrew J. Martin [Royaume-Uni] ; Safa Al-Sarraj [Royaume-Uni] ; Christopher Chandler [Royaume-Uni] ; Ho-Keung Ng [République populaire de Chine] ; Xingang Li [République populaire de Chine] ; Kun Mu [République populaire de Chine] ; Saoussen Trabelsi [Tunisie] ; Dorra H Ida-Ben Brahim [Tunisie] ; Alexei N. Kisljakov [Russie] ; Dmitry M. Konovalov [Russie] ; Andrew S. Moore [Australie] ; Angel Montero Carcaboso [Espagne] ; Mariona Sunol [Espagne] ; Carmen De Torres [Espagne] ; Ofelia Cruz [Espagne] ; Jaume Mora [Espagne] ; Ludmila I. Shats [Russie] ; João N. Stavale [Brésil] ; Lucas T. Bidinotto [Brésil] ; Rui M. Reis [Brésil, Portugal] ; Natacha Entz-Werle [France] ; Michael Farrell [Irlande (pays)] ; Jane Cryan [Irlande (pays)] ; Darach Crimmins [Irlande (pays)] ; John Caird [Irlande (pays)] ; Jane Pears [Irlande (pays)] ; Michelle Monje [États-Unis] ; Marie-Anne Debily [France] ; David Castel [France] ; Jacques Grill [France] ; Cynthia Hawkins [Canada] ; Hamid Nikbakht [Canada] ; Nada Jabado [États-Unis] ; Suzanne J. Baker [États-Unis] ; Stefan M. Pfister [Allemagne] ; David T. W. Jones [Allemagne] ; Maryam Fouladi [États-Unis] ; André O. Von Bueren [Allemagne, Suisse] ; Michael Baudis [Suisse] ; Adam Resnick [États-Unis] ; Chris Jones [Royaume-Uni]Source :
- Cancer Cell [ 1535-6108 ] ; 2017.
Descripteurs français
- KwdFr :
- ADN topoisomérases de type I (génétique), Adolescent, Dosage génique, Enfant, Enfant d'âge préscolaire, Exome, Femelle, Gliome (anatomopathologie), Gliome (génétique), Histone (génétique), Humains, Jeune adulte, Mutation, Mâle, Nourrisson, Nouveau-né, Protéines F-box (génétique), Protéines de répression (génétique), Protéines du cycle cellulaire (génétique), Protéines proto-oncogènes (génétique), Tumeurs du tronc cérébral (anatomopathologie), Tumeurs du tronc cérébral (génétique), Ubiquitin-protein ligases (génétique).
- MESH :
- anatomopathologie : Gliome, Tumeurs du tronc cérébral.
- génétique : ADN topoisomérases de type I, Gliome, Histone, Protéines F-box, Protéines de répression, Protéines du cycle cellulaire, Protéines proto-oncogènes, Tumeurs du tronc cérébral, Ubiquitin-protein ligases.
- Adolescent, Dosage génique, Enfant, Enfant d'âge préscolaire, Exome, Femelle, Humains, Jeune adulte, Mutation, Mâle, Nourrisson, Nouveau-né.
English descriptors
- KwdEn :
- Adolescent, Brain Stem Neoplasms (genetics), Brain Stem Neoplasms (pathology), Cell Cycle Proteins (genetics), Child, Child, Preschool, DNA Topoisomerases, Type I (genetics), Exome, F-Box Proteins (genetics), Female, Gene Dosage, Glioma (genetics), Glioma (pathology), Histones (genetics), Humans, Infant, Infant, Newborn, Male, Mutation, Proto-Oncogene Proteins (genetics), Repressor Proteins (genetics), Ubiquitin-Protein Ligases (genetics), Young Adult.
- MESH :
- chemical , genetics : Cell Cycle Proteins, DNA Topoisomerases, Type I, F-Box Proteins, Histones, Proto-Oncogene Proteins, Repressor Proteins, Ubiquitin-Protein Ligases.
- genetics : Brain Stem Neoplasms, Glioma.
- pathology : Brain Stem Neoplasms, Glioma.
- Adolescent, Child, Child, Preschool, Exome, Female, Gene Dosage, Humans, Infant, Infant, Newborn, Male, Mutation, Young Adult.
Abstract
We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse intrinsic pontine glioma and 20 publicly available datasets in an integrated analysis of >1,000 cases. We identified co-segregating mutations in histone-mutant subgroups including loss of
Url:
DOI: 10.1016/j.ccell.2017.08.017
PubMed: 28966033
PubMed Central: 5637314
Affiliations:
- Allemagne, Australie, Brésil, Canada, Espagne, France, Irlande (pays), Portugal, Royaume-Uni, Russie, République populaire de Chine, Suisse, Tunisie, États-Unis
- Alsace (région administrative), Angleterre, Bade-Wurtemberg, Californie, Canton de Genève, Canton de Zurich, Catalogne, District de Karlsruhe, District fédéral central, Grand Est, Grand Londres, Ohio, Pennsylvanie, Québec, Région Nord (Portugal), Tennessee, État de São Paulo
- Barcelone, Braga, Genève, Heidelberg, Londres, Montréal, Moscou, Sha Tin, Strasbourg, São Paulo, Zurich
- Université McGill, Université chinoise de Hong Kong, Université de Genève, Université de São Paulo, Université de Zurich, Université du Minho
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002363
- to stream Pmc, to step Curation: 002213
- to stream Pmc, to step Checkpoint: 000239
- to stream PubMed, to step Corpus: 000398
- to stream PubMed, to step Curation: 000396
- to stream PubMed, to step Checkpoint: 000396
- to stream Ncbi, to step Merge: 004F64
- to stream Ncbi, to step Curation: 004F64
- to stream Ncbi, to step Checkpoint: 004F64
- to stream Main, to step Merge: 000966
- to stream Main, to step Curation: 000971
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma</title><author><name sortKey="Mackay, Alan" sort="Mackay, Alan" uniqKey="Mackay A" first="Alan" last="Mackay">Alan Mackay</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burford, Anna" sort="Burford, Anna" uniqKey="Burford A" first="Anna" last="Burford">Anna Burford</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Carvalho, Diana" sort="Carvalho, Diana" uniqKey="Carvalho D" first="Diana" last="Carvalho">Diana Carvalho</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Izquierdo, Elisa" sort="Izquierdo, Elisa" uniqKey="Izquierdo E" first="Elisa" last="Izquierdo">Elisa Izquierdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fazal Salom, Janat" sort="Fazal Salom, Janat" uniqKey="Fazal Salom J" first="Janat" last="Fazal-Salom">Janat Fazal-Salom</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Taylor, Kathryn R" sort="Taylor, Kathryn R" uniqKey="Taylor K" first="Kathryn R." last="Taylor">Kathryn R. Taylor</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Stanford University School of Medicine, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bjerke, Lynn" sort="Bjerke, Lynn" uniqKey="Bjerke L" first="Lynn" last="Bjerke">Lynn Bjerke</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Clarke, Matthew" sort="Clarke, Matthew" uniqKey="Clarke M" first="Matthew" last="Clarke">Matthew Clarke</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Vinci, Mara" sort="Vinci, Mara" uniqKey="Vinci M" first="Mara" last="Vinci">Mara Vinci</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nandhabalan, Meera" sort="Nandhabalan, Meera" uniqKey="Nandhabalan M" first="Meera" last="Nandhabalan">Meera Nandhabalan</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Temelso, Sara" sort="Temelso, Sara" uniqKey="Temelso S" first="Sara" last="Temelso">Sara Temelso</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Popov, Sergey" sort="Popov, Sergey" uniqKey="Popov S" first="Sergey" last="Popov">Sergey Popov</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Cellular Pathology, University Hospital of Wales, Cardiff, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cellular Pathology, University Hospital of Wales, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Molinari, Valeria" sort="Molinari, Valeria" uniqKey="Molinari V" first="Valeria" last="Molinari">Valeria Molinari</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Raman, Pichai" sort="Raman, Pichai" uniqKey="Raman P" first="Pichai" last="Raman">Pichai Raman</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff6">Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Waanders, Angela J" sort="Waanders, Angela J" uniqKey="Waanders A" first="Angela J." last="Waanders">Angela J. Waanders</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Han, Harry J" sort="Han, Harry J" uniqKey="Han H" first="Harry J." last="Han">Harry J. Han</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Gupta, Saumya" sort="Gupta, Saumya" uniqKey="Gupta S" first="Saumya" last="Gupta">Saumya Gupta</name><affiliation wicri:level="4"><nlm:aff id="aff8">Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Marshall, Lynley" sort="Marshall, Lynley" uniqKey="Marshall L" first="Lynley" last="Marshall">Lynley Marshall</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Zacharoulis, Stergios" sort="Zacharoulis, Stergios" uniqKey="Zacharoulis S" first="Stergios" last="Zacharoulis">Stergios Zacharoulis</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Vaidya, Sucheta" sort="Vaidya, Sucheta" uniqKey="Vaidya S" first="Sucheta" last="Vaidya">Sucheta Vaidya</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Mandeville, Henry C" sort="Mandeville, Henry C" uniqKey="Mandeville H" first="Henry C." last="Mandeville">Henry C. Mandeville</name><affiliation wicri:level="1"><nlm:aff id="aff10">Department of Radiotherapy, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Radiotherapy, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Bridges, Leslie R" sort="Bridges, Leslie R" uniqKey="Bridges L" first="Leslie R." last="Bridges">Leslie R. Bridges</name><affiliation wicri:level="3"><nlm:aff id="aff11">Department of Cellular Pathology, St George's Hospital NHS Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cellular Pathology, St George's Hospital NHS Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Martin, Andrew J" sort="Martin, Andrew J" uniqKey="Martin A" first="Andrew J." last="Martin">Andrew J. Martin</name><affiliation wicri:level="3"><nlm:aff id="aff12">Department of Neurosurgery, St George's Hospital NHS Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurosurgery, St George's Hospital NHS Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Al Sarraj, Safa" sort="Al Sarraj, Safa" uniqKey="Al Sarraj S" first="Safa" last="Al-Sarraj">Safa Al-Sarraj</name><affiliation wicri:level="3"><nlm:aff id="aff13">Department of Neuropathology, Kings College Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neuropathology, Kings College Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Chandler, Christopher" sort="Chandler, Christopher" uniqKey="Chandler C" first="Christopher" last="Chandler">Christopher Chandler</name><affiliation wicri:level="3"><nlm:aff id="aff14">Department of Neurosurgery, Kings College Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurosurgery, Kings College Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ng, Ho Keung" sort="Ng, Ho Keung" uniqKey="Ng H" first="Ho-Keung" last="Ng">Ho-Keung Ng</name><affiliation wicri:level="4"><nlm:aff id="aff15">Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Li, Xingang" sort="Li, Xingang" uniqKey="Li X" first="Xingang" last="Li">Xingang Li</name><affiliation wicri:level="1"><nlm:aff id="aff16">Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan</wicri:regionArea><wicri:noRegion>Jinan</wicri:noRegion></affiliation></author><author><name sortKey="Mu, Kun" sort="Mu, Kun" uniqKey="Mu K" first="Kun" last="Mu">Kun Mu</name><affiliation wicri:level="1"><nlm:aff id="aff17">Department of Pathology, Shandong University School of Medicine, Jinan, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pathology, Shandong University School of Medicine, Jinan</wicri:regionArea><wicri:noRegion>Jinan</wicri:noRegion></affiliation></author><author><name sortKey="Trabelsi, Saoussen" sort="Trabelsi, Saoussen" uniqKey="Trabelsi S" first="Saoussen" last="Trabelsi">Saoussen Trabelsi</name><affiliation wicri:level="1"><nlm:aff id="aff18">Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse</wicri:regionArea><wicri:noRegion>Sousse</wicri:noRegion></affiliation></author><author><name sortKey="Brahim, Dorra H Ida Ben" sort="Brahim, Dorra H Ida Ben" uniqKey="Brahim D" first="Dorra H Ida-Ben" last="Brahim">Dorra H Ida-Ben Brahim</name><affiliation wicri:level="1"><nlm:aff id="aff18">Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse</wicri:regionArea><wicri:noRegion>Sousse</wicri:noRegion></affiliation></author><author><name sortKey="Kisljakov, Alexei N" sort="Kisljakov, Alexei N" uniqKey="Kisljakov A" first="Alexei N." last="Kisljakov">Alexei N. Kisljakov</name><affiliation wicri:level="3"><nlm:aff id="aff19">Department of Pathology, Morozov Children's Hospital, Moscow, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Pathology, Morozov Children's Hospital, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Konovalov, Dmitry M" sort="Konovalov, Dmitry M" uniqKey="Konovalov D" first="Dmitry M." last="Konovalov">Dmitry M. Konovalov</name><affiliation wicri:level="3"><nlm:aff id="aff20">Department of Pathology, Dmitrii Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Pathology, Dmitrii Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology and Immunology, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Moore, Andrew S" sort="Moore, Andrew S" uniqKey="Moore A" first="Andrew S." last="Moore">Andrew S. Moore</name><affiliation wicri:level="1"><nlm:aff id="aff21">UQ Child Health Research Centre, The University of Queensland, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>UQ Child Health Research Centre, The University of Queensland, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff22">Oncology Services Group, Children's Health Queensland Hospital and Health Service, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Oncology Services Group, Children's Health Queensland Hospital and Health Service, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff23">The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Carcaboso, Angel Montero" sort="Carcaboso, Angel Montero" uniqKey="Carcaboso A" first="Angel Montero" last="Carcaboso">Angel Montero Carcaboso</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Sunol, Mariona" sort="Sunol, Mariona" uniqKey="Sunol M" first="Mariona" last="Sunol">Mariona Sunol</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="De Torres, Carmen" sort="De Torres, Carmen" uniqKey="De Torres C" first="Carmen" last="De Torres">Carmen De Torres</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Cruz, Ofelia" sort="Cruz, Ofelia" uniqKey="Cruz O" first="Ofelia" last="Cruz">Ofelia Cruz</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Mora, Jaume" sort="Mora, Jaume" uniqKey="Mora J" first="Jaume" last="Mora">Jaume Mora</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Shats, Ludmila I" sort="Shats, Ludmila I" uniqKey="Shats L" first="Ludmila I." last="Shats">Ludmila I. Shats</name><affiliation wicri:level="1"><nlm:aff id="aff25">Division of Oncology, Pediatric Oncology and Radiotherapy, St Petersburg State Pediatric Medical University, St Petersburg, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Division of Oncology, Pediatric Oncology and Radiotherapy, St Petersburg State Pediatric Medical University, St Petersburg</wicri:regionArea><wicri:noRegion>St Petersburg</wicri:noRegion></affiliation></author><author><name sortKey="Stavale, Joao N" sort="Stavale, Joao N" uniqKey="Stavale J" first="João N." last="Stavale">João N. Stavale</name><affiliation wicri:level="4"><nlm:aff id="aff26">Department of Pathology, Federal University of São Paulo, São Paulo, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Pathology, Federal University of São Paulo, São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Bidinotto, Lucas T" sort="Bidinotto, Lucas T" uniqKey="Bidinotto L" first="Lucas T." last="Bidinotto">Lucas T. Bidinotto</name><affiliation wicri:level="3"><nlm:aff id="aff27">Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Reis, Rui M" sort="Reis, Rui M" uniqKey="Reis R" first="Rui M." last="Reis">Rui M. Reis</name><affiliation wicri:level="3"><nlm:aff id="aff27">Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff28">Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Braga, Portugal and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal</nlm:aff><country xml:lang="fr">Portugal</country><wicri:regionArea>Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Braga, Portugal and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães</wicri:regionArea><orgName type="university">Université du Minho</orgName><placeName><settlement type="city">Braga</settlement><region>Région Nord (Portugal)</region></placeName></affiliation></author><author><name sortKey="Entz Werle, Natacha" sort="Entz Werle, Natacha" uniqKey="Entz Werle N" first="Natacha" last="Entz-Werle">Natacha Entz-Werle</name><affiliation wicri:level="3"><nlm:aff id="aff29">Pédiatrie Onco-Hématologie - Pédiatrie III, Centre Hospitalier Régional et Universitaire Hautepierre, Strasbourg, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Pédiatrie Onco-Hématologie - Pédiatrie III, Centre Hospitalier Régional et Universitaire Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Farrell, Michael" sort="Farrell, Michael" uniqKey="Farrell M" first="Michael" last="Farrell">Michael Farrell</name><affiliation wicri:level="1"><nlm:aff id="aff30">Histopathology Department, Beaumont Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Histopathology Department, Beaumont Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Cryan, Jane" sort="Cryan, Jane" uniqKey="Cryan J" first="Jane" last="Cryan">Jane Cryan</name><affiliation wicri:level="1"><nlm:aff id="aff30">Histopathology Department, Beaumont Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Histopathology Department, Beaumont Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Crimmins, Darach" sort="Crimmins, Darach" uniqKey="Crimmins D" first="Darach" last="Crimmins">Darach Crimmins</name><affiliation wicri:level="1"><nlm:aff id="aff31">Department of Neurosurgery, Temple Street Children's University Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Neurosurgery, Temple Street Children's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Caird, John" sort="Caird, John" uniqKey="Caird J" first="John" last="Caird">John Caird</name><affiliation wicri:level="1"><nlm:aff id="aff31">Department of Neurosurgery, Temple Street Children's University Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Neurosurgery, Temple Street Children's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Pears, Jane" sort="Pears, Jane" uniqKey="Pears J" first="Jane" last="Pears">Jane Pears</name><affiliation wicri:level="1"><nlm:aff id="aff32">Department of Paediatric Oncology, Our Lady's Children's Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Paediatric Oncology, Our Lady's Children's Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Monje, Michelle" sort="Monje, Michelle" uniqKey="Monje M" first="Michelle" last="Monje">Michelle Monje</name><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Stanford University School of Medicine, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Debily, Marie Anne" sort="Debily, Marie Anne" uniqKey="Debily M" first="Marie-Anne" last="Debily">Marie-Anne Debily</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Castel, David" sort="Castel, David" uniqKey="Castel D" first="David" last="Castel">David Castel</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Grill, Jacques" sort="Grill, Jacques" uniqKey="Grill J" first="Jacques" last="Grill">Jacques Grill</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Hawkins, Cynthia" sort="Hawkins, Cynthia" uniqKey="Hawkins C" first="Cynthia" last="Hawkins">Cynthia Hawkins</name><affiliation wicri:level="1"><nlm:aff id="aff34">Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Nikbakht, Hamid" sort="Nikbakht, Hamid" uniqKey="Nikbakht H" first="Hamid" last="Nikbakht">Hamid Nikbakht</name><affiliation wicri:level="4"><nlm:aff id="aff35">Department of Pediatrics, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pediatrics, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Jabado, Nada" sort="Jabado, Nada" uniqKey="Jabado N" first="Nada" last="Jabado">Nada Jabado</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Baker, Suzanne J" sort="Baker, Suzanne J" uniqKey="Baker S" first="Suzanne J." last="Baker">Suzanne J. Baker</name><affiliation wicri:level="2"><nlm:aff id="aff36">Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Pfister, Stefan M" sort="Pfister, Stefan M" uniqKey="Pfister S" first="Stefan M." last="Pfister">Stefan M. Pfister</name><affiliation wicri:level="3"><nlm:aff id="aff37">Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff38">Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff43">Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Jones, David T W" sort="Jones, David T W" uniqKey="Jones D" first="David T. W." last="Jones">David T. W. Jones</name><affiliation wicri:level="3"><nlm:aff id="aff37">Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff43">Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Fouladi, Maryam" sort="Fouladi, Maryam" uniqKey="Fouladi M" first="Maryam" last="Fouladi">Maryam Fouladi</name><affiliation wicri:level="2"><nlm:aff id="aff39">Department of Pediatrics, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Von Bueren, Andre O" sort="Von Bueren, Andre O" uniqKey="Von Bueren A" first="André O." last="Von Bueren">André O. Von Bueren</name><affiliation wicri:level="1"><nlm:aff id="aff40">Department of Pediatrics, Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatrics, Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff41">Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff42">Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva</wicri:regionArea><orgName type="university">Université de Genève</orgName><placeName><settlement type="city">Genève</settlement><region nuts="3" type="region">Canton de Genève</region></placeName></affiliation></author><author><name sortKey="Baudis, Michael" sort="Baudis, Michael" uniqKey="Baudis M" first="Michael" last="Baudis">Michael Baudis</name><affiliation wicri:level="4"><nlm:aff id="aff8">Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Resnick, Adam" sort="Resnick, Adam" uniqKey="Resnick A" first="Adam" last="Resnick">Adam Resnick</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff6">Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Jones, Chris" sort="Jones, Chris" uniqKey="Jones C" first="Chris" last="Jones">Chris Jones</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28966033</idno><idno type="pmc">5637314</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637314</idno><idno type="RBID">PMC:5637314</idno><idno type="doi">10.1016/j.ccell.2017.08.017</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">002363</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002363</idno><idno type="wicri:Area/Pmc/Curation">002213</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002213</idno><idno type="wicri:Area/Pmc/Checkpoint">000239</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000239</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000398</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000398</idno><idno type="wicri:Area/PubMed/Curation">000396</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000396</idno><idno type="wicri:Area/PubMed/Checkpoint">000396</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000396</idno><idno type="wicri:Area/Ncbi/Merge">004F64</idno><idno type="wicri:Area/Ncbi/Curation">004F64</idno><idno type="wicri:Area/Ncbi/Checkpoint">004F64</idno><idno type="wicri:doubleKey">1535-6108:2017:Mackay A:integrated:molecular:meta</idno><idno type="wicri:Area/Main/Merge">000966</idno><idno type="wicri:Area/Main/Curation">000971</idno><idno type="wicri:Area/Main/Exploration">000971</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma</title><author><name sortKey="Mackay, Alan" sort="Mackay, Alan" uniqKey="Mackay A" first="Alan" last="Mackay">Alan Mackay</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burford, Anna" sort="Burford, Anna" uniqKey="Burford A" first="Anna" last="Burford">Anna Burford</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Carvalho, Diana" sort="Carvalho, Diana" uniqKey="Carvalho D" first="Diana" last="Carvalho">Diana Carvalho</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Izquierdo, Elisa" sort="Izquierdo, Elisa" uniqKey="Izquierdo E" first="Elisa" last="Izquierdo">Elisa Izquierdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fazal Salom, Janat" sort="Fazal Salom, Janat" uniqKey="Fazal Salom J" first="Janat" last="Fazal-Salom">Janat Fazal-Salom</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Taylor, Kathryn R" sort="Taylor, Kathryn R" uniqKey="Taylor K" first="Kathryn R." last="Taylor">Kathryn R. Taylor</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Stanford University School of Medicine, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bjerke, Lynn" sort="Bjerke, Lynn" uniqKey="Bjerke L" first="Lynn" last="Bjerke">Lynn Bjerke</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Clarke, Matthew" sort="Clarke, Matthew" uniqKey="Clarke M" first="Matthew" last="Clarke">Matthew Clarke</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Vinci, Mara" sort="Vinci, Mara" uniqKey="Vinci M" first="Mara" last="Vinci">Mara Vinci</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nandhabalan, Meera" sort="Nandhabalan, Meera" uniqKey="Nandhabalan M" first="Meera" last="Nandhabalan">Meera Nandhabalan</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Temelso, Sara" sort="Temelso, Sara" uniqKey="Temelso S" first="Sara" last="Temelso">Sara Temelso</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Popov, Sergey" sort="Popov, Sergey" uniqKey="Popov S" first="Sergey" last="Popov">Sergey Popov</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Cellular Pathology, University Hospital of Wales, Cardiff, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cellular Pathology, University Hospital of Wales, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Molinari, Valeria" sort="Molinari, Valeria" uniqKey="Molinari V" first="Valeria" last="Molinari">Valeria Molinari</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Raman, Pichai" sort="Raman, Pichai" uniqKey="Raman P" first="Pichai" last="Raman">Pichai Raman</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff6">Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Waanders, Angela J" sort="Waanders, Angela J" uniqKey="Waanders A" first="Angela J." last="Waanders">Angela J. Waanders</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Han, Harry J" sort="Han, Harry J" uniqKey="Han H" first="Harry J." last="Han">Harry J. Han</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Gupta, Saumya" sort="Gupta, Saumya" uniqKey="Gupta S" first="Saumya" last="Gupta">Saumya Gupta</name><affiliation wicri:level="4"><nlm:aff id="aff8">Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Marshall, Lynley" sort="Marshall, Lynley" uniqKey="Marshall L" first="Lynley" last="Marshall">Lynley Marshall</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Zacharoulis, Stergios" sort="Zacharoulis, Stergios" uniqKey="Zacharoulis S" first="Stergios" last="Zacharoulis">Stergios Zacharoulis</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Vaidya, Sucheta" sort="Vaidya, Sucheta" uniqKey="Vaidya S" first="Sucheta" last="Vaidya">Sucheta Vaidya</name><affiliation wicri:level="1"><nlm:aff id="aff9">Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Pediatric Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Mandeville, Henry C" sort="Mandeville, Henry C" uniqKey="Mandeville H" first="Henry C." last="Mandeville">Henry C. Mandeville</name><affiliation wicri:level="1"><nlm:aff id="aff10">Department of Radiotherapy, Royal Marsden Hospital, Sutton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Radiotherapy, Royal Marsden Hospital, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Bridges, Leslie R" sort="Bridges, Leslie R" uniqKey="Bridges L" first="Leslie R." last="Bridges">Leslie R. Bridges</name><affiliation wicri:level="3"><nlm:aff id="aff11">Department of Cellular Pathology, St George's Hospital NHS Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cellular Pathology, St George's Hospital NHS Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Martin, Andrew J" sort="Martin, Andrew J" uniqKey="Martin A" first="Andrew J." last="Martin">Andrew J. Martin</name><affiliation wicri:level="3"><nlm:aff id="aff12">Department of Neurosurgery, St George's Hospital NHS Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurosurgery, St George's Hospital NHS Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Al Sarraj, Safa" sort="Al Sarraj, Safa" uniqKey="Al Sarraj S" first="Safa" last="Al-Sarraj">Safa Al-Sarraj</name><affiliation wicri:level="3"><nlm:aff id="aff13">Department of Neuropathology, Kings College Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neuropathology, Kings College Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Chandler, Christopher" sort="Chandler, Christopher" uniqKey="Chandler C" first="Christopher" last="Chandler">Christopher Chandler</name><affiliation wicri:level="3"><nlm:aff id="aff14">Department of Neurosurgery, Kings College Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Neurosurgery, Kings College Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ng, Ho Keung" sort="Ng, Ho Keung" uniqKey="Ng H" first="Ho-Keung" last="Ng">Ho-Keung Ng</name><affiliation wicri:level="4"><nlm:aff id="aff15">Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Li, Xingang" sort="Li, Xingang" uniqKey="Li X" first="Xingang" last="Li">Xingang Li</name><affiliation wicri:level="1"><nlm:aff id="aff16">Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan</wicri:regionArea><wicri:noRegion>Jinan</wicri:noRegion></affiliation></author><author><name sortKey="Mu, Kun" sort="Mu, Kun" uniqKey="Mu K" first="Kun" last="Mu">Kun Mu</name><affiliation wicri:level="1"><nlm:aff id="aff17">Department of Pathology, Shandong University School of Medicine, Jinan, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pathology, Shandong University School of Medicine, Jinan</wicri:regionArea><wicri:noRegion>Jinan</wicri:noRegion></affiliation></author><author><name sortKey="Trabelsi, Saoussen" sort="Trabelsi, Saoussen" uniqKey="Trabelsi S" first="Saoussen" last="Trabelsi">Saoussen Trabelsi</name><affiliation wicri:level="1"><nlm:aff id="aff18">Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse</wicri:regionArea><wicri:noRegion>Sousse</wicri:noRegion></affiliation></author><author><name sortKey="Brahim, Dorra H Ida Ben" sort="Brahim, Dorra H Ida Ben" uniqKey="Brahim D" first="Dorra H Ida-Ben" last="Brahim">Dorra H Ida-Ben Brahim</name><affiliation wicri:level="1"><nlm:aff id="aff18">Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Department of Cytogenetics and Reproductive Biology, Farhat Hached Hospital, Sousse</wicri:regionArea><wicri:noRegion>Sousse</wicri:noRegion></affiliation></author><author><name sortKey="Kisljakov, Alexei N" sort="Kisljakov, Alexei N" uniqKey="Kisljakov A" first="Alexei N." last="Kisljakov">Alexei N. Kisljakov</name><affiliation wicri:level="3"><nlm:aff id="aff19">Department of Pathology, Morozov Children's Hospital, Moscow, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Pathology, Morozov Children's Hospital, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Konovalov, Dmitry M" sort="Konovalov, Dmitry M" uniqKey="Konovalov D" first="Dmitry M." last="Konovalov">Dmitry M. Konovalov</name><affiliation wicri:level="3"><nlm:aff id="aff20">Department of Pathology, Dmitrii Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Department of Pathology, Dmitrii Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology and Immunology, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Moore, Andrew S" sort="Moore, Andrew S" uniqKey="Moore A" first="Andrew S." last="Moore">Andrew S. Moore</name><affiliation wicri:level="1"><nlm:aff id="aff21">UQ Child Health Research Centre, The University of Queensland, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>UQ Child Health Research Centre, The University of Queensland, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff22">Oncology Services Group, Children's Health Queensland Hospital and Health Service, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Oncology Services Group, Children's Health Queensland Hospital and Health Service, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff23">The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Carcaboso, Angel Montero" sort="Carcaboso, Angel Montero" uniqKey="Carcaboso A" first="Angel Montero" last="Carcaboso">Angel Montero Carcaboso</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Sunol, Mariona" sort="Sunol, Mariona" uniqKey="Sunol M" first="Mariona" last="Sunol">Mariona Sunol</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="De Torres, Carmen" sort="De Torres, Carmen" uniqKey="De Torres C" first="Carmen" last="De Torres">Carmen De Torres</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Cruz, Ofelia" sort="Cruz, Ofelia" uniqKey="Cruz O" first="Ofelia" last="Cruz">Ofelia Cruz</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Mora, Jaume" sort="Mora, Jaume" uniqKey="Mora J" first="Jaume" last="Mora">Jaume Mora</name><affiliation wicri:level="3"><nlm:aff id="aff24">Institut de Recerca Sant Joan de Deu, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca Sant Joan de Deu, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Shats, Ludmila I" sort="Shats, Ludmila I" uniqKey="Shats L" first="Ludmila I." last="Shats">Ludmila I. Shats</name><affiliation wicri:level="1"><nlm:aff id="aff25">Division of Oncology, Pediatric Oncology and Radiotherapy, St Petersburg State Pediatric Medical University, St Petersburg, Russian Federation</nlm:aff><country xml:lang="fr">Russie</country><wicri:regionArea>Division of Oncology, Pediatric Oncology and Radiotherapy, St Petersburg State Pediatric Medical University, St Petersburg</wicri:regionArea><wicri:noRegion>St Petersburg</wicri:noRegion></affiliation></author><author><name sortKey="Stavale, Joao N" sort="Stavale, Joao N" uniqKey="Stavale J" first="João N." last="Stavale">João N. Stavale</name><affiliation wicri:level="4"><nlm:aff id="aff26">Department of Pathology, Federal University of São Paulo, São Paulo, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Pathology, Federal University of São Paulo, São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Bidinotto, Lucas T" sort="Bidinotto, Lucas T" uniqKey="Bidinotto L" first="Lucas T." last="Bidinotto">Lucas T. Bidinotto</name><affiliation wicri:level="3"><nlm:aff id="aff27">Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Reis, Rui M" sort="Reis, Rui M" uniqKey="Reis R" first="Rui M." last="Reis">Rui M. Reis</name><affiliation wicri:level="3"><nlm:aff id="aff27">Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Molecular Oncology Research Centre, Barretos Cancer Hospital, Barretos, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff28">Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Braga, Portugal and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal</nlm:aff><country xml:lang="fr">Portugal</country><wicri:regionArea>Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Braga, Portugal and ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães</wicri:regionArea><orgName type="university">Université du Minho</orgName><placeName><settlement type="city">Braga</settlement><region>Région Nord (Portugal)</region></placeName></affiliation></author><author><name sortKey="Entz Werle, Natacha" sort="Entz Werle, Natacha" uniqKey="Entz Werle N" first="Natacha" last="Entz-Werle">Natacha Entz-Werle</name><affiliation wicri:level="3"><nlm:aff id="aff29">Pédiatrie Onco-Hématologie - Pédiatrie III, Centre Hospitalier Régional et Universitaire Hautepierre, Strasbourg, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Pédiatrie Onco-Hématologie - Pédiatrie III, Centre Hospitalier Régional et Universitaire Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Farrell, Michael" sort="Farrell, Michael" uniqKey="Farrell M" first="Michael" last="Farrell">Michael Farrell</name><affiliation wicri:level="1"><nlm:aff id="aff30">Histopathology Department, Beaumont Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Histopathology Department, Beaumont Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Cryan, Jane" sort="Cryan, Jane" uniqKey="Cryan J" first="Jane" last="Cryan">Jane Cryan</name><affiliation wicri:level="1"><nlm:aff id="aff30">Histopathology Department, Beaumont Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Histopathology Department, Beaumont Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Crimmins, Darach" sort="Crimmins, Darach" uniqKey="Crimmins D" first="Darach" last="Crimmins">Darach Crimmins</name><affiliation wicri:level="1"><nlm:aff id="aff31">Department of Neurosurgery, Temple Street Children's University Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Neurosurgery, Temple Street Children's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Caird, John" sort="Caird, John" uniqKey="Caird J" first="John" last="Caird">John Caird</name><affiliation wicri:level="1"><nlm:aff id="aff31">Department of Neurosurgery, Temple Street Children's University Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Neurosurgery, Temple Street Children's University Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Pears, Jane" sort="Pears, Jane" uniqKey="Pears J" first="Jane" last="Pears">Jane Pears</name><affiliation wicri:level="1"><nlm:aff id="aff32">Department of Paediatric Oncology, Our Lady's Children's Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Paediatric Oncology, Our Lady's Children's Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Monje, Michelle" sort="Monje, Michelle" uniqKey="Monje M" first="Michelle" last="Monje">Michelle Monje</name><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Stanford University School of Medicine, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Debily, Marie Anne" sort="Debily, Marie Anne" uniqKey="Debily M" first="Marie-Anne" last="Debily">Marie-Anne Debily</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Castel, David" sort="Castel, David" uniqKey="Castel D" first="David" last="Castel">David Castel</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Grill, Jacques" sort="Grill, Jacques" uniqKey="Grill J" first="Jacques" last="Grill">Jacques Grill</name><affiliation wicri:level="1"><nlm:aff id="aff33">Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Département de Cancerologie de l'Enfant et de l'Adolescent, Institut Gustav Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Hawkins, Cynthia" sort="Hawkins, Cynthia" uniqKey="Hawkins C" first="Cynthia" last="Hawkins">Cynthia Hawkins</name><affiliation wicri:level="1"><nlm:aff id="aff34">Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Nikbakht, Hamid" sort="Nikbakht, Hamid" uniqKey="Nikbakht H" first="Hamid" last="Nikbakht">Hamid Nikbakht</name><affiliation wicri:level="4"><nlm:aff id="aff35">Department of Pediatrics, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pediatrics, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Jabado, Nada" sort="Jabado, Nada" uniqKey="Jabado N" first="Nada" last="Jabado">Nada Jabado</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Baker, Suzanne J" sort="Baker, Suzanne J" uniqKey="Baker S" first="Suzanne J." last="Baker">Suzanne J. Baker</name><affiliation wicri:level="2"><nlm:aff id="aff36">Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Pfister, Stefan M" sort="Pfister, Stefan M" uniqKey="Pfister S" first="Stefan M." last="Pfister">Stefan M. Pfister</name><affiliation wicri:level="3"><nlm:aff id="aff37">Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff38">Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff43">Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Jones, David T W" sort="Jones, David T W" uniqKey="Jones D" first="David T. W." last="Jones">David T. W. Jones</name><affiliation wicri:level="3"><nlm:aff id="aff37">Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff43">Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Fouladi, Maryam" sort="Fouladi, Maryam" uniqKey="Fouladi M" first="Maryam" last="Fouladi">Maryam Fouladi</name><affiliation wicri:level="2"><nlm:aff id="aff39">Department of Pediatrics, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pediatrics, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Von Bueren, Andre O" sort="Von Bueren, Andre O" uniqKey="Von Bueren A" first="André O." last="Von Bueren">André O. Von Bueren</name><affiliation wicri:level="1"><nlm:aff id="aff40">Department of Pediatrics, Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pediatrics, Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff41">Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff42">Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva</wicri:regionArea><orgName type="university">Université de Genève</orgName><placeName><settlement type="city">Genève</settlement><region nuts="3" type="region">Canton de Genève</region></placeName></affiliation></author><author><name sortKey="Baudis, Michael" sort="Baudis, Michael" uniqKey="Baudis M" first="Michael" last="Baudis">Michael Baudis</name><affiliation wicri:level="4"><nlm:aff id="aff8">Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Molecular Life Sciences, Swiss Institute of Bioinformatics, University of Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region><settlement type="city">Zurich</settlement></placeName><orgName type="university">Université de Zurich</orgName></affiliation></author><author><name sortKey="Resnick, Adam" sort="Resnick, Adam" uniqKey="Resnick A" first="Adam" last="Resnick">Adam Resnick</name><affiliation wicri:level="2"><nlm:aff id="aff5">The Center for Data Driven Discovery in Biomedicine (D<sup>3</sup>b), Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>b), Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff6">Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Jones, Chris" sort="Jones, Chris" uniqKey="Jones C" first="Chris" last="Jones">Chris Jones</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Molecular Pathology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Molecular Pathology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Therapeutics, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">Cancer Cell</title><idno type="ISSN">1535-6108</idno><idno type="eISSN">1878-3686</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Brain Stem Neoplasms (genetics)</term><term>Brain Stem Neoplasms (pathology)</term><term>Cell Cycle Proteins (genetics)</term><term>Child</term><term>Child, Preschool</term><term>DNA Topoisomerases, Type I (genetics)</term><term>Exome</term><term>F-Box Proteins (genetics)</term><term>Female</term><term>Gene Dosage</term><term>Glioma (genetics)</term><term>Glioma (pathology)</term><term>Histones (genetics)</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Mutation</term><term>Proto-Oncogene Proteins (genetics)</term><term>Repressor Proteins (genetics)</term><term>Ubiquitin-Protein Ligases (genetics)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ADN topoisomérases de type I (génétique)</term><term>Adolescent</term><term>Dosage génique</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Exome</term><term>Femelle</term><term>Gliome (anatomopathologie)</term><term>Gliome (génétique)</term><term>Histone (génétique)</term><term>Humains</term><term>Jeune adulte</term><term>Mutation</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term><term>Protéines F-box (génétique)</term><term>Protéines de répression (génétique)</term><term>Protéines du cycle cellulaire (génétique)</term><term>Protéines proto-oncogènes (génétique)</term><term>Tumeurs du tronc cérébral (anatomopathologie)</term><term>Tumeurs du tronc cérébral (génétique)</term><term>Ubiquitin-protein ligases (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cell Cycle Proteins</term><term>DNA Topoisomerases, Type I</term><term>F-Box Proteins</term><term>Histones</term><term>Proto-Oncogene Proteins</term><term>Repressor Proteins</term><term>Ubiquitin-Protein Ligases</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Gliome</term><term>Tumeurs du tronc cérébral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Brain Stem Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN topoisomérases de type I</term><term>Gliome</term><term>Histone</term><term>Protéines F-box</term><term>Protéines de répression</term><term>Protéines du cycle cellulaire</term><term>Protéines proto-oncogènes</term><term>Tumeurs du tronc cérébral</term><term>Ubiquitin-protein ligases</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain Stem Neoplasms</term><term>Glioma</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Child</term><term>Child, Preschool</term><term>Exome</term><term>Female</term><term>Gene Dosage</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term><term>Mutation</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Dosage génique</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Exome</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mutation</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse intrinsic pontine glioma and 20 publicly available datasets in an integrated analysis of >1,000 cases. We identified co-segregating mutations in histone-mutant subgroups including loss of <italic>FBXW7</italic> in H3.3G34R/V, <italic>TOP3A</italic> rearrangements in H3.3K27M, and <italic>BCOR</italic> mutations in H3.1K27M. Histone wild-type subgroups are refined by the presence of key oncogenic events or methylation profiles more closely resembling lower-grade tumors. Genomic aberrations increase with age, highlighting the infant population as biologically and clinically distinct. Uncommon pathway dysregulation is seen in small subsets of tumors, further defining the molecular diversity of the disease, opening up avenues for biological study and providing a basis for functionally defined future treatment stratification.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Baker, S J" uniqKey="Baker S">S.J. Baker</name></author><author><name sortKey="Ellison, D W" uniqKey="Ellison D">D.W. Ellison</name></author><author><name sortKey="Gutmann, D H" uniqKey="Gutmann D">D.H. Gutmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barrow, J" uniqKey="Barrow J">J. Barrow</name></author><author><name sortKey="Adamowicz Brice, M" uniqKey="Adamowicz Brice M">M. Adamowicz-Brice</name></author><author><name sortKey="Cartmill, M" uniqKey="Cartmill M">M. Cartmill</name></author><author><name sortKey="Macarthur, D" uniqKey="Macarthur D">D. MacArthur</name></author><author><name sortKey="Lowe, J" uniqKey="Lowe J">J. Lowe</name></author><author><name sortKey="Robson, K" uniqKey="Robson K">K. Robson</name></author><author><name sortKey="Brundler, M A" uniqKey="Brundler M">M.A. Brundler</name></author><author><name sortKey="Walker, D A" uniqKey="Walker D">D.A. Walker</name></author><author><name sortKey="Coyle, B" uniqKey="Coyle B">B. Coyle</name></author><author><name sortKey="Grundy, R" uniqKey="Grundy R">R. Grundy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bax, D A" uniqKey="Bax D">D.A. Bax</name></author><author><name sortKey="Mackay, A" uniqKey="Mackay A">A. Mackay</name></author><author><name sortKey="Little, S E" uniqKey="Little S">S.E. Little</name></author><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author><author><name sortKey="Viana Pereira, M" uniqKey="Viana Pereira M">M. Viana-Pereira</name></author><author><name sortKey="Tamber, N" uniqKey="Tamber N">N. Tamber</name></author><author><name sortKey="Grigoriadis, A E" uniqKey="Grigoriadis A">A.E. Grigoriadis</name></author><author><name sortKey="Ashworth, A" uniqKey="Ashworth A">A. Ashworth</name></author><author><name sortKey="Reis, R M" uniqKey="Reis R">R.M. Reis</name></author><author><name sortKey="Ellison, D W" uniqKey="Ellison D">D.W. Ellison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bender, S" uniqKey="Bender S">S. Bender</name></author><author><name sortKey="Tang, Y" uniqKey="Tang Y">Y. Tang</name></author><author><name sortKey="Lindroth, A M" uniqKey="Lindroth A">A.M. Lindroth</name></author><author><name sortKey="Hovestadt, V" uniqKey="Hovestadt V">V. Hovestadt</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Kool, M" uniqKey="Kool M">M. Kool</name></author><author><name sortKey="Zapatka, M" uniqKey="Zapatka M">M. Zapatka</name></author><author><name sortKey="Northcott, P A" uniqKey="Northcott P">P.A. Northcott</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bjerke, L" uniqKey="Bjerke L">L. Bjerke</name></author><author><name sortKey="Mackay, A" uniqKey="Mackay A">A. Mackay</name></author><author><name sortKey="Nandhabalan, M" uniqKey="Nandhabalan M">M. Nandhabalan</name></author><author><name sortKey="Burford, A" uniqKey="Burford A">A. Burford</name></author><author><name sortKey="Jury, A" uniqKey="Jury A">A. Jury</name></author><author><name sortKey="Popov, S" uniqKey="Popov S">S. Popov</name></author><author><name sortKey="Bax, D A" uniqKey="Bax D">D.A. Bax</name></author><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author><author><name sortKey="Taylor, K R" uniqKey="Taylor K">K.R. Taylor</name></author><author><name sortKey="Vinci, M" uniqKey="Vinci M">M. Vinci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bouffet, E" uniqKey="Bouffet E">E. Bouffet</name></author><author><name sortKey="Larouche, V" uniqKey="Larouche V">V. Larouche</name></author><author><name sortKey="Campbell, B B" uniqKey="Campbell B">B.B. Campbell</name></author><author><name sortKey="Merico, D" uniqKey="Merico D">D. Merico</name></author><author><name sortKey="De Borja, R" uniqKey="De Borja R">R. de Borja</name></author><author><name sortKey="Aronson, M" uniqKey="Aronson M">M. Aronson</name></author><author><name sortKey="Durno, C" uniqKey="Durno C">C. Durno</name></author><author><name sortKey="Krueger, J" uniqKey="Krueger J">J. Krueger</name></author><author><name sortKey="Cabric, V" uniqKey="Cabric V">V. Cabric</name></author><author><name sortKey="Ramaswamy, V" uniqKey="Ramaswamy V">V. Ramaswamy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buczkowicz, P" uniqKey="Buczkowicz P">P. Buczkowicz</name></author><author><name sortKey="Hoeman, C" uniqKey="Hoeman C">C. Hoeman</name></author><author><name sortKey="Rakopoulos, P" uniqKey="Rakopoulos P">P. Rakopoulos</name></author><author><name sortKey="Pajovic, S" uniqKey="Pajovic S">S. Pajovic</name></author><author><name sortKey="Letourneau, L" uniqKey="Letourneau L">L. Letourneau</name></author><author><name sortKey="Dzamba, M" uniqKey="Dzamba M">M. Dzamba</name></author><author><name sortKey="Morrison, A" uniqKey="Morrison A">A. Morrison</name></author><author><name sortKey="Lewis, P" uniqKey="Lewis P">P. Lewis</name></author><author><name sortKey="Bouffet, E" uniqKey="Bouffet E">E. Bouffet</name></author><author><name sortKey="Bartels, U" uniqKey="Bartels U">U. Bartels</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cai, H" uniqKey="Cai H">H. Cai</name></author><author><name sortKey="Kumar, N" uniqKey="Kumar N">N. Kumar</name></author><author><name sortKey="Baudis, M" uniqKey="Baudis M">M. Baudis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cai, H" uniqKey="Cai H">H. Cai</name></author><author><name sortKey="Kumar, N" uniqKey="Kumar N">N. Kumar</name></author><author><name sortKey="Ai, N" uniqKey="Ai N">N. Ai</name></author><author><name sortKey="Gupta, S" uniqKey="Gupta S">S. Gupta</name></author><author><name sortKey="Rath, P" uniqKey="Rath P">P. Rath</name></author><author><name sortKey="Baudis, M" uniqKey="Baudis M">M. Baudis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author><author><name sortKey="Mackay, A" uniqKey="Mackay A">A. Mackay</name></author><author><name sortKey="Bjerke, L" uniqKey="Bjerke L">L. Bjerke</name></author><author><name sortKey="Grundy, R G" uniqKey="Grundy R">R.G. Grundy</name></author><author><name sortKey="Lopes, C" uniqKey="Lopes C">C. Lopes</name></author><author><name sortKey="Reis, R M" uniqKey="Reis R">R.M. Reis</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Castel, D" uniqKey="Castel D">D. Castel</name></author><author><name sortKey="Philippe, C" uniqKey="Philippe C">C. Philippe</name></author><author><name sortKey="Calmon, R" uniqKey="Calmon R">R. Calmon</name></author><author><name sortKey="Le Dret, L" uniqKey="Le Dret L">L. Le Dret</name></author><author><name sortKey="Truffaux, N" uniqKey="Truffaux N">N. Truffaux</name></author><author><name sortKey="Boddaert, N" uniqKey="Boddaert N">N. Boddaert</name></author><author><name sortKey="Pages, M" uniqKey="Pages M">M. Pages</name></author><author><name sortKey="Taylor, K R" uniqKey="Taylor K">K.R. Taylor</name></author><author><name sortKey="Saulnier, P" uniqKey="Saulnier P">P. Saulnier</name></author><author><name sortKey="Lacroix, L" uniqKey="Lacroix L">L. Lacroix</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ceccarelli, M" uniqKey="Ceccarelli M">M. Ceccarelli</name></author><author><name sortKey="Barthel, F P" uniqKey="Barthel F">F.P. Barthel</name></author><author><name sortKey="Malta, T M" uniqKey="Malta T">T.M. Malta</name></author><author><name sortKey="Sabedot, T S" uniqKey="Sabedot T">T.S. Sabedot</name></author><author><name sortKey="Salama, S R" uniqKey="Salama S">S.R. Salama</name></author><author><name sortKey="Murray, B A" uniqKey="Murray B">B.A. Murray</name></author><author><name sortKey="Morozova, O" uniqKey="Morozova O">O. Morozova</name></author><author><name sortKey="Newton, Y" uniqKey="Newton Y">Y. Newton</name></author><author><name sortKey="Radenbaugh, A" uniqKey="Radenbaugh A">A. Radenbaugh</name></author><author><name sortKey="Pagnotta, S M" uniqKey="Pagnotta S">S.M. Pagnotta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, K M" uniqKey="Chan K">K.M. Chan</name></author><author><name sortKey="Fang, D" uniqKey="Fang D">D. Fang</name></author><author><name sortKey="Gan, H" uniqKey="Gan H">H. Gan</name></author><author><name sortKey="Hashizume, R" uniqKey="Hashizume R">R. Hashizume</name></author><author><name sortKey="Yu, C" uniqKey="Yu C">C. Yu</name></author><author><name sortKey="Schroeder, M" uniqKey="Schroeder M">M. Schroeder</name></author><author><name sortKey="Gupta, N" uniqKey="Gupta N">N. Gupta</name></author><author><name sortKey="Mueller, S" uniqKey="Mueller S">S. Mueller</name></author><author><name sortKey="James, C D" uniqKey="James C">C.D. James</name></author><author><name sortKey="Jenkins, R" uniqKey="Jenkins R">R. Jenkins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, R J" uniqKey="Davis R">R.J. Davis</name></author><author><name sortKey="Welcker, M" uniqKey="Welcker M">M. Welcker</name></author><author><name sortKey="Clurman, B E" uniqKey="Clurman B">B.E. Clurman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fontebasso, A M" uniqKey="Fontebasso A">A.M. Fontebasso</name></author><author><name sortKey="Schwartzentruber, J" uniqKey="Schwartzentruber J">J. Schwartzentruber</name></author><author><name sortKey="Khuong Quang, D A" uniqKey="Khuong Quang D">D.A. Khuong-Quang</name></author><author><name sortKey="Liu, X Y" uniqKey="Liu X">X.Y. Liu</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Korshunov, A" uniqKey="Korshunov A">A. Korshunov</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Witt, H" uniqKey="Witt H">H. Witt</name></author><author><name sortKey="Kool, M" uniqKey="Kool M">M. Kool</name></author><author><name sortKey="Albrecht, S" uniqKey="Albrecht S">S. Albrecht</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fontebasso, A M" uniqKey="Fontebasso A">A.M. Fontebasso</name></author><author><name sortKey="Papillon Cavanagh, S" uniqKey="Papillon Cavanagh S">S. Papillon-Cavanagh</name></author><author><name sortKey="Schwartzentruber, J" uniqKey="Schwartzentruber J">J. Schwartzentruber</name></author><author><name sortKey="Nikbakht, H" uniqKey="Nikbakht H">H. Nikbakht</name></author><author><name sortKey="Gerges, N" uniqKey="Gerges N">N. Gerges</name></author><author><name sortKey="Fiset, P O" uniqKey="Fiset P">P.O. Fiset</name></author><author><name sortKey="Bechet, D" uniqKey="Bechet D">D. Bechet</name></author><author><name sortKey="Faury, D" uniqKey="Faury D">D. Faury</name></author><author><name sortKey="De Jay, N" uniqKey="De Jay N">N. De Jay</name></author><author><name sortKey="Ramkissoon, L A" uniqKey="Ramkissoon L">L.A. Ramkissoon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Funato, K" uniqKey="Funato K">K. Funato</name></author><author><name sortKey="Major, T" uniqKey="Major T">T. Major</name></author><author><name sortKey="Lewis, P W" uniqKey="Lewis P">P.W. Lewis</name></author><author><name sortKey="Allis, C D" uniqKey="Allis C">C.D. Allis</name></author><author><name sortKey="Tabar, V" uniqKey="Tabar V">V. Tabar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grasso, C S" uniqKey="Grasso C">C.S. Grasso</name></author><author><name sortKey="Tang, Y" uniqKey="Tang Y">Y. Tang</name></author><author><name sortKey="Truffaux, N" uniqKey="Truffaux N">N. Truffaux</name></author><author><name sortKey="Berlow, N E" uniqKey="Berlow N">N.E. Berlow</name></author><author><name sortKey="Liu, L" uniqKey="Liu L">L. Liu</name></author><author><name sortKey="Debily, M A" uniqKey="Debily M">M.A. Debily</name></author><author><name sortKey="Quist, M J" uniqKey="Quist M">M.J. Quist</name></author><author><name sortKey="Davis, L E" uniqKey="Davis L">L.E. Davis</name></author><author><name sortKey="Huang, E C" uniqKey="Huang E">E.C. Huang</name></author><author><name sortKey="Woo, P J" uniqKey="Woo P">P.J. Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hennika, T" uniqKey="Hennika T">T. Hennika</name></author><author><name sortKey="Hu, G" uniqKey="Hu G">G. Hu</name></author><author><name sortKey="Olaciregui, N G" uniqKey="Olaciregui N">N.G. Olaciregui</name></author><author><name sortKey="Barton, K L" uniqKey="Barton K">K.L. Barton</name></author><author><name sortKey="Ehteda, A" uniqKey="Ehteda A">A. Ehteda</name></author><author><name sortKey="Chitranjan, A" uniqKey="Chitranjan A">A. Chitranjan</name></author><author><name sortKey="Chang, C" uniqKey="Chang C">C. Chang</name></author><author><name sortKey="Gifford, A J" uniqKey="Gifford A">A.J. Gifford</name></author><author><name sortKey="Tsoli, M" uniqKey="Tsoli M">M. Tsoli</name></author><author><name sortKey="Ziegler, D S" uniqKey="Ziegler D">D.S. Ziegler</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Baker, S J" uniqKey="Baker S">S.J. Baker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Perryman, L" uniqKey="Perryman L">L. Perryman</name></author><author><name sortKey="Hargrave, D" uniqKey="Hargrave D">D. Hargrave</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Karajannis, M A" uniqKey="Karajannis M">M.A. Karajannis</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Kieran, M W" uniqKey="Kieran M">M.W. Kieran</name></author><author><name sortKey="Monje, M" uniqKey="Monje M">M. Monje</name></author><author><name sortKey="Baker, S J" uniqKey="Baker S">S.J. Baker</name></author><author><name sortKey="Becher, O J" uniqKey="Becher O">O.J. Becher</name></author><author><name sortKey="Cho, Y J" uniqKey="Cho Y">Y.J. Cho</name></author><author><name sortKey="Gupta, N" uniqKey="Gupta N">N. Gupta</name></author><author><name sortKey="Hawkins, C" uniqKey="Hawkins C">C. Hawkins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khuong Quang, D A" uniqKey="Khuong Quang D">D.A. Khuong-Quang</name></author><author><name sortKey="Buczkowicz, P" uniqKey="Buczkowicz P">P. Buczkowicz</name></author><author><name sortKey="Rakopoulos, P" uniqKey="Rakopoulos P">P. Rakopoulos</name></author><author><name sortKey="Liu, X Y" uniqKey="Liu X">X.Y. Liu</name></author><author><name sortKey="Fontebasso, A M" uniqKey="Fontebasso A">A.M. Fontebasso</name></author><author><name sortKey="Bouffet, E" uniqKey="Bouffet E">E. Bouffet</name></author><author><name sortKey="Bartels, U" uniqKey="Bartels U">U. Bartels</name></author><author><name sortKey="Albrecht, S" uniqKey="Albrecht S">S. Albrecht</name></author><author><name sortKey="Schwartzentruber, J" uniqKey="Schwartzentruber J">J. Schwartzentruber</name></author><author><name sortKey="Letourneau, L" uniqKey="Letourneau L">L. Letourneau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Korshunov, A" uniqKey="Korshunov A">A. Korshunov</name></author><author><name sortKey="Ryzhova, M" uniqKey="Ryzhova M">M. Ryzhova</name></author><author><name sortKey="Hovestadt, V" uniqKey="Hovestadt V">V. Hovestadt</name></author><author><name sortKey="Bender, S" uniqKey="Bender S">S. Bender</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Capper, D" uniqKey="Capper D">D. Capper</name></author><author><name sortKey="Meyer, J" uniqKey="Meyer J">J. Meyer</name></author><author><name sortKey="Schrimpf, D" uniqKey="Schrimpf D">D. Schrimpf</name></author><author><name sortKey="Kool, M" uniqKey="Kool M">M. Kool</name></author><author><name sortKey="Northcott, P A" uniqKey="Northcott P">P.A. Northcott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Korshunov, A" uniqKey="Korshunov A">A. Korshunov</name></author><author><name sortKey="Schrimpf, D" uniqKey="Schrimpf D">D. Schrimpf</name></author><author><name sortKey="Ryzhova, M" uniqKey="Ryzhova M">M. Ryzhova</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Chavez, L" uniqKey="Chavez L">L. Chavez</name></author><author><name sortKey="Hovestadt, V" uniqKey="Hovestadt V">V. Hovestadt</name></author><author><name sortKey="Sharma, T" uniqKey="Sharma T">T. Sharma</name></author><author><name sortKey="Habel, A" uniqKey="Habel A">A. Habel</name></author><author><name sortKey="Burford, A" uniqKey="Burford A">A. Burford</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kramm, C M" uniqKey="Kramm C">C.M. Kramm</name></author><author><name sortKey="Butenhoff, S" uniqKey="Butenhoff S">S. Butenhoff</name></author><author><name sortKey="Rausche, U" uniqKey="Rausche U">U. Rausche</name></author><author><name sortKey="Warmuth Metz, M" uniqKey="Warmuth Metz M">M. Warmuth-Metz</name></author><author><name sortKey="Kortmann, R D" uniqKey="Kortmann R">R.D. Kortmann</name></author><author><name sortKey="Pietsch, T" uniqKey="Pietsch T">T. Pietsch</name></author><author><name sortKey="Gnekow, A" uniqKey="Gnekow A">A. Gnekow</name></author><author><name sortKey="Jorch, N" uniqKey="Jorch N">N. Jorch</name></author><author><name sortKey="Janssen, G" uniqKey="Janssen G">G. Janssen</name></author><author><name sortKey="Berthold, F" uniqKey="Berthold F">F. Berthold</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louis, D N" uniqKey="Louis D">D.N. Louis</name></author><author><name sortKey="Perry, A" uniqKey="Perry A">A. Perry</name></author><author><name sortKey="Reifenberger, G" uniqKey="Reifenberger G">G. Reifenberger</name></author><author><name sortKey="Von Deimling, A" uniqKey="Von Deimling A">A. von Deimling</name></author><author><name sortKey="Figarella Branger, D" uniqKey="Figarella Branger D">D. Figarella-Branger</name></author><author><name sortKey="Cavenee, W K" uniqKey="Cavenee W">W.K. Cavenee</name></author><author><name sortKey="Ohgaki, H" uniqKey="Ohgaki H">H. Ohgaki</name></author><author><name sortKey="Wiestler, O D" uniqKey="Wiestler O">O.D. Wiestler</name></author><author><name sortKey="Kleihues, P" uniqKey="Kleihues P">P. Kleihues</name></author><author><name sortKey="Ellison, D W" uniqKey="Ellison D">D.W. Ellison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicolaides, T P" uniqKey="Nicolaides T">T.P. Nicolaides</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Solomon, D A" uniqKey="Solomon D">D.A. Solomon</name></author><author><name sortKey="Hariono, S" uniqKey="Hariono S">S. Hariono</name></author><author><name sortKey="Hashizume, R" uniqKey="Hashizume R">R. Hashizume</name></author><author><name sortKey="Barkovich, K" uniqKey="Barkovich K">K. Barkovich</name></author><author><name sortKey="Baker, S J" uniqKey="Baker S">S.J. Baker</name></author><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Forshew, T" uniqKey="Forshew T">T. Forshew</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Northcott, P A" uniqKey="Northcott P">P.A. Northcott</name></author><author><name sortKey="Lee, C" uniqKey="Lee C">C. Lee</name></author><author><name sortKey="Zichner, T" uniqKey="Zichner T">T. Zichner</name></author><author><name sortKey="Stutz, A M" uniqKey="Stutz A">A.M. Stutz</name></author><author><name sortKey="Erkek, S" uniqKey="Erkek S">S. Erkek</name></author><author><name sortKey="Kawauchi, D" uniqKey="Kawauchi D">D. Kawauchi</name></author><author><name sortKey="Shih, D J" uniqKey="Shih D">D.J. Shih</name></author><author><name sortKey="Hovestadt, V" uniqKey="Hovestadt V">V. Hovestadt</name></author><author><name sortKey="Zapatka, M" uniqKey="Zapatka M">M. Zapatka</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ostrom, Q T" uniqKey="Ostrom Q">Q.T. Ostrom</name></author><author><name sortKey="Gittleman, H" uniqKey="Gittleman H">H. Gittleman</name></author><author><name sortKey="Fulop, J" uniqKey="Fulop J">J. Fulop</name></author><author><name sortKey="Liu, M" uniqKey="Liu M">M. Liu</name></author><author><name sortKey="Blanda, R" uniqKey="Blanda R">R. Blanda</name></author><author><name sortKey="Kromer, C" uniqKey="Kromer C">C. Kromer</name></author><author><name sortKey="Wolinsky, Y" uniqKey="Wolinsky Y">Y. Wolinsky</name></author><author><name sortKey="Kruchko, C" uniqKey="Kruchko C">C. Kruchko</name></author><author><name sortKey="Barnholtz Sloan, J S" uniqKey="Barnholtz Sloan J">J.S. Barnholtz-Sloan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Qu, C" uniqKey="Qu C">C. Qu</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z. Liu</name></author><author><name sortKey="Adamowicz Brice, M" uniqKey="Adamowicz Brice M">M. Adamowicz-Brice</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Bax, D A" uniqKey="Bax D">D.A. Bax</name></author><author><name sortKey="Coyle, B" uniqKey="Coyle B">B. Coyle</name></author><author><name sortKey="Barrow, J" uniqKey="Barrow J">J. Barrow</name></author><author><name sortKey="Hargrave, D" uniqKey="Hargrave D">D. Hargrave</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Broniscer, A" uniqKey="Broniscer A">A. Broniscer</name></author><author><name sortKey="Qu, C" uniqKey="Qu C">C. Qu</name></author><author><name sortKey="Miller, C P" uniqKey="Miller C">C.P. Miller</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Tatevossian, R G" uniqKey="Tatevossian R">R.G. Tatevossian</name></author><author><name sortKey="Olson, J M" uniqKey="Olson J">J.M. Olson</name></author><author><name sortKey="Geyer, J R" uniqKey="Geyer J">J.R. Geyer</name></author><author><name sortKey="Chi, S N" uniqKey="Chi S">S.N. Chi</name></author><author><name sortKey="Da Silva, N S" uniqKey="Da Silva N">N.S. da Silva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Zhu, X" uniqKey="Zhu X">X. Zhu</name></author><author><name sortKey="Qu, C" uniqKey="Qu C">C. Qu</name></author><author><name sortKey="Endersby, R" uniqKey="Endersby R">R. Endersby</name></author><author><name sortKey="Diaz, A K" uniqKey="Diaz A">A.K. Diaz</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Bax, D A" uniqKey="Bax D">D.A. Bax</name></author><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author><author><name sortKey="Reis, R M" uniqKey="Reis R">R.M. Reis</name></author><author><name sortKey="Onar Thomas, A" uniqKey="Onar Thomas A">A. Onar-Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puget, S" uniqKey="Puget S">S. Puget</name></author><author><name sortKey="Philippe, C" uniqKey="Philippe C">C. Philippe</name></author><author><name sortKey="Bax, D A" uniqKey="Bax D">D.A. Bax</name></author><author><name sortKey="Job, B" uniqKey="Job B">B. Job</name></author><author><name sortKey="Varlet, P" uniqKey="Varlet P">P. Varlet</name></author><author><name sortKey="Junier, M P" uniqKey="Junier M">M.P. Junier</name></author><author><name sortKey="Andreiuolo, F" uniqKey="Andreiuolo F">F. Andreiuolo</name></author><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author><author><name sortKey="Reis, R" uniqKey="Reis R">R. Reis</name></author><author><name sortKey="Guerrini Rousseau, L" uniqKey="Guerrini Rousseau L">L. Guerrini-Rousseau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qin, E Y" uniqKey="Qin E">E.Y. Qin</name></author><author><name sortKey="Cooper, D D" uniqKey="Cooper D">D.D. Cooper</name></author><author><name sortKey="Abbott, K L" uniqKey="Abbott K">K.L. Abbott</name></author><author><name sortKey="Lennon, J" uniqKey="Lennon J">J. Lennon</name></author><author><name sortKey="Nagaraja, S" uniqKey="Nagaraja S">S. Nagaraja</name></author><author><name sortKey="Mackay, A" uniqKey="Mackay A">A. Mackay</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Vogel, H" uniqKey="Vogel H">H. Vogel</name></author><author><name sortKey="Jackson, P K" uniqKey="Jackson P">P.K. Jackson</name></author><author><name sortKey="Monje, M" uniqKey="Monje M">M. Monje</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richards, M W" uniqKey="Richards M">M.W. Richards</name></author><author><name sortKey="Burgess, S G" uniqKey="Burgess S">S.G. Burgess</name></author><author><name sortKey="Poon, E" uniqKey="Poon E">E. Poon</name></author><author><name sortKey="Carstensen, A" uniqKey="Carstensen A">A. Carstensen</name></author><author><name sortKey="Eilers, M" uniqKey="Eilers M">M. Eilers</name></author><author><name sortKey="Chesler, L" uniqKey="Chesler L">L. Chesler</name></author><author><name sortKey="Bayliss, R" uniqKey="Bayliss R">R. Bayliss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schiffman, J D" uniqKey="Schiffman J">J.D. Schiffman</name></author><author><name sortKey="Hodgson, J G" uniqKey="Hodgson J">J.G. Hodgson</name></author><author><name sortKey="Vandenberg, S R" uniqKey="Vandenberg S">S.R. VandenBerg</name></author><author><name sortKey="Flaherty, P" uniqKey="Flaherty P">P. Flaherty</name></author><author><name sortKey="Polley, M Y" uniqKey="Polley M">M.Y. Polley</name></author><author><name sortKey="Yu, M" uniqKey="Yu M">M. Yu</name></author><author><name sortKey="Fisher, P G" uniqKey="Fisher P">P.G. Fisher</name></author><author><name sortKey="Rowitch, D H" uniqKey="Rowitch D">D.H. Rowitch</name></author><author><name sortKey="Ford, J M" uniqKey="Ford J">J.M. Ford</name></author><author><name sortKey="Berger, M S" uniqKey="Berger M">M.S. Berger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwartzentruber, J" uniqKey="Schwartzentruber J">J. Schwartzentruber</name></author><author><name sortKey="Korshunov, A" uniqKey="Korshunov A">A. Korshunov</name></author><author><name sortKey="Liu, X Y" uniqKey="Liu X">X.Y. Liu</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Pfaff, E" uniqKey="Pfaff E">E. Pfaff</name></author><author><name sortKey="Jacob, K" uniqKey="Jacob K">K. Jacob</name></author><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Fontebasso, A M" uniqKey="Fontebasso A">A.M. Fontebasso</name></author><author><name sortKey="Quang, D A" uniqKey="Quang D">D.A. Quang</name></author><author><name sortKey="Tonjes, M" uniqKey="Tonjes M">M. Tonjes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shlien, A" uniqKey="Shlien A">A. Shlien</name></author><author><name sortKey="Campbell, B B" uniqKey="Campbell B">B.B. Campbell</name></author><author><name sortKey="De Borja, R" uniqKey="De Borja R">R. de Borja</name></author><author><name sortKey="Alexandrov, L B" uniqKey="Alexandrov L">L.B. Alexandrov</name></author><author><name sortKey="Merico, D" uniqKey="Merico D">D. Merico</name></author><author><name sortKey="Wedge, D" uniqKey="Wedge D">D. Wedge</name></author><author><name sortKey="Van Loo, P" uniqKey="Van Loo P">P. Van Loo</name></author><author><name sortKey="Tarpey, P S" uniqKey="Tarpey P">P.S. Tarpey</name></author><author><name sortKey="Coupland, P" uniqKey="Coupland P">P. Coupland</name></author><author><name sortKey="Behjati, S" uniqKey="Behjati S">S. Behjati</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Witt, H" uniqKey="Witt H">H. Witt</name></author><author><name sortKey="Hovestadt, V" uniqKey="Hovestadt V">V. Hovestadt</name></author><author><name sortKey="Khuong Quang, D A" uniqKey="Khuong Quang D">D.A. Khuong-Quang</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Konermann, C" uniqKey="Konermann C">C. Konermann</name></author><author><name sortKey="Pfaff, E" uniqKey="Pfaff E">E. Pfaff</name></author><author><name sortKey="Tonjes, M" uniqKey="Tonjes M">M. Tonjes</name></author><author><name sortKey="Sill, M" uniqKey="Sill M">M. Sill</name></author><author><name sortKey="Bender, S" uniqKey="Bender S">S. Bender</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sturm, D" uniqKey="Sturm D">D. Sturm</name></author><author><name sortKey="Bender, S" uniqKey="Bender S">S. Bender</name></author><author><name sortKey="Jones, D T" uniqKey="Jones D">D.T. Jones</name></author><author><name sortKey="Lichter, P" uniqKey="Lichter P">P. Lichter</name></author><author><name sortKey="Grill, J" uniqKey="Grill J">J. Grill</name></author><author><name sortKey="Becher, O" uniqKey="Becher O">O. Becher</name></author><author><name sortKey="Hawkins, C" uniqKey="Hawkins C">C. Hawkins</name></author><author><name sortKey="Majewski, J" uniqKey="Majewski J">J. Majewski</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author><author><name sortKey="Costello, J F" uniqKey="Costello J">J.F. Costello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, K R" uniqKey="Taylor K">K.R. Taylor</name></author><author><name sortKey="Mackay, A" uniqKey="Mackay A">A. Mackay</name></author><author><name sortKey="Truffaux, N" uniqKey="Truffaux N">N. Truffaux</name></author><author><name sortKey="Butterfield, Y S" uniqKey="Butterfield Y">Y.S. Butterfield</name></author><author><name sortKey="Morozova, O" uniqKey="Morozova O">O. Morozova</name></author><author><name sortKey="Philippe, C" uniqKey="Philippe C">C. Philippe</name></author><author><name sortKey="Castel, D" uniqKey="Castel D">D. Castel</name></author><author><name sortKey="Grasso, C S" uniqKey="Grasso C">C.S. Grasso</name></author><author><name sortKey="Vinci, M" uniqKey="Vinci M">M. Vinci</name></author><author><name sortKey="Carvalho, D" uniqKey="Carvalho D">D. Carvalho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, K R" uniqKey="Taylor K">K.R. Taylor</name></author><author><name sortKey="Vinci, M" uniqKey="Vinci M">M. Vinci</name></author><author><name sortKey="Bullock, A N" uniqKey="Bullock A">A.N. Bullock</name></author><author><name sortKey="Jones, C" uniqKey="Jones C">C. Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Temime Smaali, N" uniqKey="Temime Smaali N">N. Temime-Smaali</name></author><author><name sortKey="Guittat, L" uniqKey="Guittat L">L. Guittat</name></author><author><name sortKey="Wenner, T" uniqKey="Wenner T">T. Wenner</name></author><author><name sortKey="Bayart, E" uniqKey="Bayart E">E. Bayart</name></author><author><name sortKey="Douarre, C" uniqKey="Douarre C">C. Douarre</name></author><author><name sortKey="Gomez, D" uniqKey="Gomez D">D. Gomez</name></author><author><name sortKey="Giraud Panis, M J" uniqKey="Giraud Panis M">M.J. Giraud-Panis</name></author><author><name sortKey="Londono Vallejo, A" uniqKey="Londono Vallejo A">A. Londono-Vallejo</name></author><author><name sortKey="Gilson, E" uniqKey="Gilson E">E. Gilson</name></author><author><name sortKey="Amor Gueret, M" uniqKey="Amor Gueret M">M. Amor-Gueret</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Temime Smaali, N" uniqKey="Temime Smaali N">N. Temime-Smaali</name></author><author><name sortKey="Guittat, L" uniqKey="Guittat L">L. Guittat</name></author><author><name sortKey="Sidibe, A" uniqKey="Sidibe A">A. Sidibe</name></author><author><name sortKey="Shin Ya, K" uniqKey="Shin Ya K">K. Shin-ya</name></author><author><name sortKey="Trentesaux, C" uniqKey="Trentesaux C">C. Trentesaux</name></author><author><name sortKey="Riou, J F" uniqKey="Riou J">J.F. Riou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tiberi, L" uniqKey="Tiberi L">L. Tiberi</name></author><author><name sortKey="Bonnefont, J" uniqKey="Bonnefont J">J. Bonnefont</name></author><author><name sortKey="Van Den Ameele, J" uniqKey="Van Den Ameele J">J. van den Ameele</name></author><author><name sortKey="Le Bon, S D" uniqKey="Le Bon S">S.D. Le Bon</name></author><author><name sortKey="Herpoel, A" uniqKey="Herpoel A">A. Herpoel</name></author><author><name sortKey="Bilheu, A" uniqKey="Bilheu A">A. Bilheu</name></author><author><name sortKey="Baron, B W" uniqKey="Baron B">B.W. Baron</name></author><author><name sortKey="Vanderhaeghen, P" uniqKey="Vanderhaeghen P">P. Vanderhaeghen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Venkatesh, H S" uniqKey="Venkatesh H">H.S. Venkatesh</name></author><author><name sortKey="Johung, T B" uniqKey="Johung T">T.B. Johung</name></author><author><name sortKey="Caretti, V" uniqKey="Caretti V">V. Caretti</name></author><author><name sortKey="Noll, A" uniqKey="Noll A">A. Noll</name></author><author><name sortKey="Tang, Y" uniqKey="Tang Y">Y. Tang</name></author><author><name sortKey="Nagaraja, S" uniqKey="Nagaraja S">S. Nagaraja</name></author><author><name sortKey="Gibson, E M" uniqKey="Gibson E">E.M. Gibson</name></author><author><name sortKey="Mount, C W" uniqKey="Mount C">C.W. Mount</name></author><author><name sortKey="Polepalli, J" uniqKey="Polepalli J">J. Polepalli</name></author><author><name sortKey="Mitra, S S" uniqKey="Mitra S">S.S. Mitra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welcker, M" uniqKey="Welcker M">M. Welcker</name></author><author><name sortKey="Orian, A" uniqKey="Orian A">A. Orian</name></author><author><name sortKey="Jin, J" uniqKey="Jin J">J. Jin</name></author><author><name sortKey="Grim, J E" uniqKey="Grim J">J.E. Grim</name></author><author><name sortKey="Harper, J W" uniqKey="Harper J">J.W. Harper</name></author><author><name sortKey="Eisenman, R N" uniqKey="Eisenman R">R.N. Eisenman</name></author><author><name sortKey="Clurman, B E" uniqKey="Clurman B">B.E. Clurman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, L" uniqKey="Wu L">L. Wu</name></author><author><name sortKey="Davies, S L" uniqKey="Davies S">S.L. Davies</name></author><author><name sortKey="North, P S" uniqKey="North P">P.S. North</name></author><author><name sortKey="Goulaouic, H" uniqKey="Goulaouic H">H. Goulaouic</name></author><author><name sortKey="Riou, J F" uniqKey="Riou J">J.F. Riou</name></author><author><name sortKey="Turley, H" uniqKey="Turley H">H. Turley</name></author><author><name sortKey="Gatter, K C" uniqKey="Gatter K">K.C. Gatter</name></author><author><name sortKey="Hickson, I D" uniqKey="Hickson I">I.D. Hickson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, G" uniqKey="Wu G">G. Wu</name></author><author><name sortKey="Broniscer, A" uniqKey="Broniscer A">A. Broniscer</name></author><author><name sortKey="Mceachron, T A" uniqKey="Mceachron T">T.A. McEachron</name></author><author><name sortKey="Lu, C" uniqKey="Lu C">C. Lu</name></author><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Becksfort, J" uniqKey="Becksfort J">J. Becksfort</name></author><author><name sortKey="Qu, C" uniqKey="Qu C">C. Qu</name></author><author><name sortKey="Ding, L" uniqKey="Ding L">L. Ding</name></author><author><name sortKey="Huether, R" uniqKey="Huether R">R. Huether</name></author><author><name sortKey="Parker, M" uniqKey="Parker M">M. Parker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, G" uniqKey="Wu G">G. Wu</name></author><author><name sortKey="Diaz, A K" uniqKey="Diaz A">A.K. Diaz</name></author><author><name sortKey="Paugh, B S" uniqKey="Paugh B">B.S. Paugh</name></author><author><name sortKey="Rankin, S L" uniqKey="Rankin S">S.L. Rankin</name></author><author><name sortKey="Ju, B" uniqKey="Ju B">B. Ju</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Zhu, X" uniqKey="Zhu X">X. Zhu</name></author><author><name sortKey="Qu, C" uniqKey="Qu C">C. Qu</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yada, M" uniqKey="Yada M">M. Yada</name></author><author><name sortKey="Hatakeyama, S" uniqKey="Hatakeyama S">S. Hatakeyama</name></author><author><name sortKey="Kamura, T" uniqKey="Kamura T">T. Kamura</name></author><author><name sortKey="Nishiyama, M" uniqKey="Nishiyama M">M. Nishiyama</name></author><author><name sortKey="Tsunematsu, R" uniqKey="Tsunematsu R">R. Tsunematsu</name></author><author><name sortKey="Imaki, H" uniqKey="Imaki H">H. Imaki</name></author><author><name sortKey="Ishida, N" uniqKey="Ishida N">N. Ishida</name></author><author><name sortKey="Okumura, F" uniqKey="Okumura F">F. Okumura</name></author><author><name sortKey="Nakayama, K" uniqKey="Nakayama K">K. Nakayama</name></author><author><name sortKey="Nakayama, K I" uniqKey="Nakayama K">K.I. Nakayama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, J" uniqKey="Yang J">J. Yang</name></author><author><name sortKey="Bachrati, C Z" uniqKey="Bachrati C">C.Z. Bachrati</name></author><author><name sortKey="Ou, J" uniqKey="Ou J">J. Ou</name></author><author><name sortKey="Hickson, I D" uniqKey="Hickson I">I.D. Hickson</name></author><author><name sortKey="Brown, G W" uniqKey="Brown G">G.W. Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zarghooni, M" uniqKey="Zarghooni M">M. Zarghooni</name></author><author><name sortKey="Bartels, U" uniqKey="Bartels U">U. Bartels</name></author><author><name sortKey="Lee, E" uniqKey="Lee E">E. Lee</name></author><author><name sortKey="Buczkowicz, P" uniqKey="Buczkowicz P">P. Buczkowicz</name></author><author><name sortKey="Morrison, A" uniqKey="Morrison A">A. Morrison</name></author><author><name sortKey="Huang, A" uniqKey="Huang A">A. Huang</name></author><author><name sortKey="Bouffet, E" uniqKey="Bouffet E">E. Bouffet</name></author><author><name sortKey="Hawkins, C" uniqKey="Hawkins C">C. Hawkins</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Brésil</li><li>Canada</li><li>Espagne</li><li>France</li><li>Irlande (pays)</li><li>Portugal</li><li>Royaume-Uni</li><li>Russie</li><li>République populaire de Chine</li><li>Suisse</li><li>Tunisie</li><li>États-Unis</li></country><region><li>Alsace (région administrative)</li><li>Angleterre</li><li>Bade-Wurtemberg</li><li>Californie</li><li>Canton de Genève</li><li>Canton de Zurich</li><li>Catalogne</li><li>District de Karlsruhe</li><li>District fédéral central</li><li>Grand Est</li><li>Grand Londres</li><li>Ohio</li><li>Pennsylvanie</li><li>Québec</li><li>Région Nord (Portugal)</li><li>Tennessee</li><li>État de São Paulo</li></region><settlement><li>Barcelone</li><li>Braga</li><li>Genève</li><li>Heidelberg</li><li>Londres</li><li>Montréal</li><li>Moscou</li><li>Sha Tin</li><li>Strasbourg</li><li>São Paulo</li><li>Zurich</li></settlement><orgName><li>Université McGill</li><li>Université chinoise de Hong Kong</li><li>Université de Genève</li><li>Université de São Paulo</li><li>Université de Zurich</li><li>Université du Minho</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mackay, Alan" sort="Mackay, Alan" uniqKey="Mackay A" first="Alan" last="Mackay">Alan Mackay</name></region><name sortKey="Al Sarraj, Safa" sort="Al Sarraj, Safa" uniqKey="Al Sarraj S" first="Safa" last="Al-Sarraj">Safa Al-Sarraj</name><name sortKey="Bjerke, Lynn" sort="Bjerke, Lynn" uniqKey="Bjerke L" first="Lynn" last="Bjerke">Lynn Bjerke</name><name sortKey="Bjerke, Lynn" sort="Bjerke, Lynn" uniqKey="Bjerke L" first="Lynn" last="Bjerke">Lynn Bjerke</name><name sortKey="Bridges, Leslie R" sort="Bridges, Leslie R" uniqKey="Bridges L" first="Leslie R." last="Bridges">Leslie R. Bridges</name><name sortKey="Burford, Anna" sort="Burford, Anna" uniqKey="Burford A" first="Anna" last="Burford">Anna Burford</name><name sortKey="Burford, Anna" sort="Burford, Anna" uniqKey="Burford A" first="Anna" last="Burford">Anna Burford</name><name sortKey="Carvalho, Diana" sort="Carvalho, Diana" uniqKey="Carvalho D" first="Diana" last="Carvalho">Diana Carvalho</name><name sortKey="Carvalho, Diana" sort="Carvalho, Diana" uniqKey="Carvalho D" first="Diana" last="Carvalho">Diana Carvalho</name><name sortKey="Chandler, Christopher" sort="Chandler, Christopher" uniqKey="Chandler C" first="Christopher" last="Chandler">Christopher Chandler</name><name sortKey="Clarke, Matthew" sort="Clarke, Matthew" uniqKey="Clarke M" first="Matthew" last="Clarke">Matthew Clarke</name><name sortKey="Clarke, Matthew" sort="Clarke, Matthew" uniqKey="Clarke M" first="Matthew" last="Clarke">Matthew Clarke</name><name sortKey="Fazal Salom, Janat" sort="Fazal Salom, Janat" uniqKey="Fazal Salom J" first="Janat" last="Fazal-Salom">Janat Fazal-Salom</name><name sortKey="Fazal Salom, Janat" sort="Fazal Salom, Janat" uniqKey="Fazal Salom J" first="Janat" last="Fazal-Salom">Janat Fazal-Salom</name><name sortKey="Izquierdo, Elisa" sort="Izquierdo, Elisa" uniqKey="Izquierdo E" first="Elisa" last="Izquierdo">Elisa Izquierdo</name><name sortKey="Izquierdo, Elisa" sort="Izquierdo, Elisa" uniqKey="Izquierdo E" first="Elisa" last="Izquierdo">Elisa Izquierdo</name><name sortKey="Jones, Chris" sort="Jones, Chris" uniqKey="Jones C" first="Chris" last="Jones">Chris Jones</name><name sortKey="Jones, Chris" sort="Jones, Chris" uniqKey="Jones C" first="Chris" last="Jones">Chris Jones</name><name sortKey="Mackay, Alan" sort="Mackay, Alan" uniqKey="Mackay A" first="Alan" last="Mackay">Alan Mackay</name><name sortKey="Mandeville, Henry C" sort="Mandeville, Henry C" uniqKey="Mandeville H" first="Henry C." last="Mandeville">Henry C. Mandeville</name><name sortKey="Marshall, Lynley" sort="Marshall, Lynley" uniqKey="Marshall L" first="Lynley" last="Marshall">Lynley Marshall</name><name sortKey="Martin, Andrew J" sort="Martin, Andrew J" uniqKey="Martin A" first="Andrew J." last="Martin">Andrew J. Martin</name><name sortKey="Molinari, Valeria" sort="Molinari, Valeria" uniqKey="Molinari V" first="Valeria" last="Molinari">Valeria Molinari</name><name sortKey="Molinari, Valeria" sort="Molinari, Valeria" uniqKey="Molinari V" first="Valeria" last="Molinari">Valeria Molinari</name><name sortKey="Nandhabalan, Meera" sort="Nandhabalan, Meera" uniqKey="Nandhabalan M" first="Meera" last="Nandhabalan">Meera Nandhabalan</name><name sortKey="Nandhabalan, Meera" sort="Nandhabalan, Meera" uniqKey="Nandhabalan M" first="Meera" last="Nandhabalan">Meera Nandhabalan</name><name sortKey="Popov, Sergey" sort="Popov, Sergey" uniqKey="Popov S" first="Sergey" last="Popov">Sergey Popov</name><name sortKey="Popov, Sergey" sort="Popov, Sergey" uniqKey="Popov S" first="Sergey" last="Popov">Sergey Popov</name><name sortKey="Popov, Sergey" sort="Popov, Sergey" uniqKey="Popov S" first="Sergey" last="Popov">Sergey Popov</name><name sortKey="Taylor, Kathryn R" sort="Taylor, Kathryn R" uniqKey="Taylor K" first="Kathryn R." last="Taylor">Kathryn R. Taylor</name><name sortKey="Taylor, Kathryn R" sort="Taylor, Kathryn R" uniqKey="Taylor K" first="Kathryn R." last="Taylor">Kathryn R. Taylor</name><name sortKey="Temelso, Sara" sort="Temelso, Sara" uniqKey="Temelso S" first="Sara" last="Temelso">Sara Temelso</name><name sortKey="Temelso, Sara" sort="Temelso, Sara" uniqKey="Temelso S" first="Sara" last="Temelso">Sara Temelso</name><name sortKey="Vaidya, Sucheta" sort="Vaidya, Sucheta" uniqKey="Vaidya S" first="Sucheta" last="Vaidya">Sucheta Vaidya</name><name sortKey="Vinci, Mara" sort="Vinci, Mara" uniqKey="Vinci M" first="Mara" last="Vinci">Mara Vinci</name><name sortKey="Vinci, Mara" sort="Vinci, Mara" uniqKey="Vinci M" first="Mara" last="Vinci">Mara Vinci</name><name sortKey="Zacharoulis, Stergios" sort="Zacharoulis, Stergios" uniqKey="Zacharoulis S" first="Stergios" last="Zacharoulis">Stergios Zacharoulis</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Taylor, Kathryn R" sort="Taylor, Kathryn R" uniqKey="Taylor K" first="Kathryn R." last="Taylor">Kathryn R. Taylor</name></region><name sortKey="Baker, Suzanne J" sort="Baker, Suzanne J" uniqKey="Baker S" first="Suzanne J." last="Baker">Suzanne J. Baker</name><name sortKey="Fouladi, Maryam" sort="Fouladi, Maryam" uniqKey="Fouladi M" first="Maryam" last="Fouladi">Maryam Fouladi</name><name sortKey="Han, Harry J" sort="Han, Harry J" uniqKey="Han H" first="Harry J." last="Han">Harry J. Han</name><name sortKey="Han, Harry J" sort="Han, Harry J" uniqKey="Han H" first="Harry J." last="Han">Harry J. Han</name><name sortKey="Jabado, Nada" sort="Jabado, Nada" uniqKey="Jabado N" first="Nada" last="Jabado">Nada Jabado</name><name sortKey="Monje, Michelle" sort="Monje, Michelle" uniqKey="Monje M" first="Michelle" last="Monje">Michelle Monje</name><name sortKey="Raman, Pichai" sort="Raman, Pichai" uniqKey="Raman P" first="Pichai" last="Raman">Pichai Raman</name><name sortKey="Raman, Pichai" sort="Raman, Pichai" uniqKey="Raman P" first="Pichai" last="Raman">Pichai Raman</name><name sortKey="Resnick, Adam" sort="Resnick, Adam" uniqKey="Resnick A" first="Adam" last="Resnick">Adam Resnick</name><name sortKey="Resnick, Adam" sort="Resnick, Adam" uniqKey="Resnick A" first="Adam" last="Resnick">Adam Resnick</name><name sortKey="Resnick, Adam" sort="Resnick, Adam" uniqKey="Resnick A" first="Adam" last="Resnick">Adam Resnick</name><name sortKey="Waanders, Angela J" sort="Waanders, Angela J" uniqKey="Waanders A" first="Angela J." last="Waanders">Angela J. Waanders</name><name sortKey="Waanders, Angela J" sort="Waanders, Angela J" uniqKey="Waanders A" first="Angela J." last="Waanders">Angela J. Waanders</name></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Gupta, Saumya" sort="Gupta, Saumya" uniqKey="Gupta S" first="Saumya" last="Gupta">Saumya Gupta</name></region><name sortKey="Baudis, Michael" sort="Baudis, Michael" uniqKey="Baudis M" first="Michael" last="Baudis">Michael Baudis</name><name sortKey="Von Bueren, Andre O" sort="Von Bueren, Andre O" uniqKey="Von Bueren A" first="André O." last="Von Bueren">André O. Von Bueren</name><name sortKey="Von Bueren, Andre O" sort="Von Bueren, Andre O" uniqKey="Von Bueren A" first="André O." last="Von Bueren">André O. Von Bueren</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Ng, Ho Keung" sort="Ng, Ho Keung" uniqKey="Ng H" first="Ho-Keung" last="Ng">Ho-Keung Ng</name></noRegion><name sortKey="Li, Xingang" sort="Li, Xingang" uniqKey="Li X" first="Xingang" last="Li">Xingang Li</name><name sortKey="Mu, Kun" sort="Mu, Kun" uniqKey="Mu K" first="Kun" last="Mu">Kun Mu</name></country><country name="Tunisie"><noRegion><name sortKey="Trabelsi, Saoussen" sort="Trabelsi, Saoussen" uniqKey="Trabelsi S" first="Saoussen" last="Trabelsi">Saoussen Trabelsi</name></noRegion><name sortKey="Brahim, Dorra H Ida Ben" sort="Brahim, Dorra H Ida Ben" uniqKey="Brahim D" first="Dorra H Ida-Ben" last="Brahim">Dorra H Ida-Ben Brahim</name></country><country name="Russie"><region name="District fédéral central"><name sortKey="Kisljakov, Alexei N" sort="Kisljakov, Alexei N" uniqKey="Kisljakov A" first="Alexei N." last="Kisljakov">Alexei N. Kisljakov</name></region><name sortKey="Konovalov, Dmitry M" sort="Konovalov, Dmitry M" uniqKey="Konovalov D" first="Dmitry M." last="Konovalov">Dmitry M. Konovalov</name><name sortKey="Shats, Ludmila I" sort="Shats, Ludmila I" uniqKey="Shats L" first="Ludmila I." last="Shats">Ludmila I. Shats</name></country><country name="Australie"><noRegion><name sortKey="Moore, Andrew S" sort="Moore, Andrew S" uniqKey="Moore A" first="Andrew S." last="Moore">Andrew S. Moore</name></noRegion><name sortKey="Moore, Andrew S" sort="Moore, Andrew S" uniqKey="Moore A" first="Andrew S." last="Moore">Andrew S. Moore</name><name sortKey="Moore, Andrew S" sort="Moore, Andrew S" uniqKey="Moore A" first="Andrew S." last="Moore">Andrew S. Moore</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Carcaboso, Angel Montero" sort="Carcaboso, Angel Montero" uniqKey="Carcaboso A" first="Angel Montero" last="Carcaboso">Angel Montero Carcaboso</name></region><name sortKey="Cruz, Ofelia" sort="Cruz, Ofelia" uniqKey="Cruz O" first="Ofelia" last="Cruz">Ofelia Cruz</name><name sortKey="De Torres, Carmen" sort="De Torres, Carmen" uniqKey="De Torres C" first="Carmen" last="De Torres">Carmen De Torres</name><name sortKey="Mora, Jaume" sort="Mora, Jaume" uniqKey="Mora J" first="Jaume" last="Mora">Jaume Mora</name><name sortKey="Sunol, Mariona" sort="Sunol, Mariona" uniqKey="Sunol M" first="Mariona" last="Sunol">Mariona Sunol</name></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Stavale, Joao N" sort="Stavale, Joao N" uniqKey="Stavale J" first="João N." last="Stavale">João N. Stavale</name></region><name sortKey="Bidinotto, Lucas T" sort="Bidinotto, Lucas T" uniqKey="Bidinotto L" first="Lucas T." last="Bidinotto">Lucas T. Bidinotto</name><name sortKey="Reis, Rui M" sort="Reis, Rui M" uniqKey="Reis R" first="Rui M." last="Reis">Rui M. Reis</name></country><country name="Portugal"><region name="Région Nord (Portugal)"><name sortKey="Reis, Rui M" sort="Reis, Rui M" uniqKey="Reis R" first="Rui M." last="Reis">Rui M. Reis</name></region></country><country name="France"><region name="Grand Est"><name sortKey="Entz Werle, Natacha" sort="Entz Werle, Natacha" uniqKey="Entz Werle N" first="Natacha" last="Entz-Werle">Natacha Entz-Werle</name></region><name sortKey="Castel, David" sort="Castel, David" uniqKey="Castel D" first="David" last="Castel">David Castel</name><name sortKey="Debily, Marie Anne" sort="Debily, Marie Anne" uniqKey="Debily M" first="Marie-Anne" last="Debily">Marie-Anne Debily</name><name sortKey="Grill, Jacques" sort="Grill, Jacques" uniqKey="Grill J" first="Jacques" last="Grill">Jacques Grill</name></country><country name="Irlande (pays)"><noRegion><name sortKey="Farrell, Michael" sort="Farrell, Michael" uniqKey="Farrell M" first="Michael" last="Farrell">Michael Farrell</name></noRegion><name sortKey="Caird, John" sort="Caird, John" uniqKey="Caird J" first="John" last="Caird">John Caird</name><name sortKey="Crimmins, Darach" sort="Crimmins, Darach" uniqKey="Crimmins D" first="Darach" last="Crimmins">Darach Crimmins</name><name sortKey="Cryan, Jane" sort="Cryan, Jane" uniqKey="Cryan J" first="Jane" last="Cryan">Jane Cryan</name><name sortKey="Pears, Jane" sort="Pears, Jane" uniqKey="Pears J" first="Jane" last="Pears">Jane Pears</name></country><country name="Canada"><noRegion><name sortKey="Hawkins, Cynthia" sort="Hawkins, Cynthia" uniqKey="Hawkins C" first="Cynthia" last="Hawkins">Cynthia Hawkins</name></noRegion><name sortKey="Nikbakht, Hamid" sort="Nikbakht, Hamid" uniqKey="Nikbakht H" first="Hamid" last="Nikbakht">Hamid Nikbakht</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Pfister, Stefan M" sort="Pfister, Stefan M" uniqKey="Pfister S" first="Stefan M." last="Pfister">Stefan M. Pfister</name></region><name sortKey="Jones, David T W" sort="Jones, David T W" uniqKey="Jones D" first="David T. W." last="Jones">David T. W. Jones</name><name sortKey="Jones, David T W" sort="Jones, David T W" uniqKey="Jones D" first="David T. W." last="Jones">David T. W. Jones</name><name sortKey="Pfister, Stefan M" sort="Pfister, Stefan M" uniqKey="Pfister S" first="Stefan M." last="Pfister">Stefan M. Pfister</name><name sortKey="Pfister, Stefan M" sort="Pfister, Stefan M" uniqKey="Pfister S" first="Stefan M." last="Pfister">Stefan M. Pfister</name><name sortKey="Von Bueren, Andre O" sort="Von Bueren, Andre O" uniqKey="Von Bueren A" first="André O." last="Von Bueren">André O. Von Bueren</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000971 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000971 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:5637314
|texte= Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28966033" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |